Related Experiment Video
Updated: Jan 1, 2026
Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
Published on: March 14, 2019
Augmented debridement for implant related chronic osteomyelitis with an absorbable, gentamycin loaded calcium
Efstathios Drampalos1, Hasan Raza Mohammad1, Anand Pillai1
1Department of Orthopaedics, Orthoplastic Unit, Wythenshawe Hospital, Manchester NHS Univeristy Foundation, NHS Trust, UK.
Abstract:
We report outcomes from 52 patients with chronic osteomyelitis from implant infection treated with a single stage protocol including debridement augmented with application of CERAMENT™/G biocomposite after resection of Cierny-Mader (C-M) stage III and IV chronic osteomyelitis. Mean age was 53 years with a mean follow up of 17 months. Infection was eradicated in 48 (92.3%) patients. There were four (7.7%) recurrences. Eighteen patients (35%) had a flap. Staphylococci (51%) and Enterococci (15%) were the commonest microorganisms. Local antibiotic augmentation (CERAMENT™/G biocomposite) with dead space management is effective in the treatment of implant related chronic osteomyelitis.
Level Of Evidence:
Prognostic Level IV.
