Related Experiment Video
Updated: Jan 1, 2026

10:12
Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
Published on: September 19, 2022
2.7K
Synthesis of NickFects, a New Family of CPPs, by Solid-Phase Peptide Synthesis
Piret Arukuusk1, Ülo Langel2,3
1Institute of Technology, Tartu University, Tartu, Estonia. piret.arukuusk@gmail.com.
Methods in Molecular Biology (Clifton, N.J.)
|December 28, 2019
Abstract:
Cell-penetrating peptides (CPPs) are relatively short peptides that can enter to the cell interior and facilitate intracellular delivery of associated cargo molecules. NickFects is a novel family of CPPs, designed to deliver various types of bio-active cargos using non-covalent nanoparticle formation approach. This chapter describes in details the manual synthesis of cell-penetrating peptides using Fmoc-solid phase peptide synthesis (SPPS).

