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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Related Experiment Video

Updated: Jan 1, 2026

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[Progress in immunotherapy for hepatocellular carcinoma].

Zongyi Shen1, Maochen Li1, Suhang Bai1

  • 1College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|December 28, 2019
PubMed
Summary

Hepatocellular carcinoma (HCC), a deadly liver cancer, is rising globally. Immunotherapy offers a promising new treatment by boosting the immune system to fight cancer cells, unlike traditional methods.

Keywords:
adoptive immunotherapyhepatocellular carcinomaimmune checkpoint treatmentimmunotherapytumor vaccine

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Area of Science:

  • Oncology
  • Immunology
  • Cancer Research

Background:

  • Hepatocellular carcinoma (HCC) presents a significant global health challenge with increasing morbidity and mortality rates.
  • China faces a particularly high burden, with the highest liver cancer death rate worldwide.
  • Traditional treatments like surgery, chemotherapy, and radiotherapy have limitations.

Purpose of the Study:

  • To review the research progress of immunotherapy for liver cancer.
  • To highlight immunotherapy as an emerging and effective cancer treatment strategy.

Main Methods:

  • Review of current research on immunotherapy for liver cancer.
  • Analysis of immunotherapy's mechanisms, including immune checkpoint inhibitors, adoptive immunotherapy, and tumor vaccines.
  • Comparison of immunotherapy with traditional cancer therapies.

Main Results:

  • Immunotherapy activates the body's immune function to control and eliminate tumor cells.
  • Key immunotherapy approaches include immune checkpoint inhibitors, adoptive immunotherapy, and tumor vaccines.
  • Immunotherapy demonstrates potential in delaying tumor progression and prolonging patient survival.

Conclusions:

  • Immunotherapy represents a significant advancement in liver cancer treatment.
  • It offers a promising alternative or adjunct to conventional therapies by enhancing anti-tumor immunity.
  • Further research and clinical application of immunotherapy are crucial for improving outcomes in HCC patients.