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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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A Modular and Diastereoselective 5 + 1 Cyclization Approach to N-(Hetero)Aryl Piperidines

Matthew A Larsen1, Elisabeth T Hennessy1, Madeleine C Deem2

  • 1Department of Discovery Chemistry , Merck & Co., Inc. , Boston , Massachusetts 02115 , United States.

Journal of the American Chemical Society
|December 28, 2019
PubMed

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