Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Carbohydrate Metabolism01:36

Carbohydrate Metabolism

13.6K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
13.6K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

4.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.2K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.0K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.0K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

804
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
804
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

4.7K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.7K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

1.9K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mismatch repair dissection by in vivo RNAi reveals dose-dependent modulators of somatic instability and proteome remodeling in Huntington's disease.

bioRxiv : the preprint server for biology·2026
Same author

Experimental evaluation of the impact of reduced anticontamination measures on the integrity of items sampled within mock crime scenes.

Science & justice : journal of the Forensic Science Society·2026
Same author

What is the potential role of the nonopioid suzetrigine in pain management?

JAAPA : official journal of the American Academy of Physician Assistants·2026
Same author

Identifying the priorities for nurse and midwife-led research: a Delphi study involving staff and patients.

Journal of research in nursing : JRN·2026
Same author

KRASG12R-Mutant Pancreatic Cancer Features Limited ERK/MAPK Transcriptional Activity and a Distinctive Tumor Microenvironment.

Cancer research·2026
Same author

Presence of phosphodiester backbone, but not nucleobases, in the guide's 3' terminal region is necessary for RISC loading and target cleavage in vitro and in vivo.

Nucleic acids research·2026

Related Experiment Video

Updated: Jan 1, 2026

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

7.2K

Bariatric surgery and type 2 diabetes.

Jennifer Stewart1, Sarah Allen, Emily Weidman-Evans

  • 1At the time this article was written, Jennifer Stewart was a student in the PA program at LSUHSC School of Allied Health in Shreveport, La. She now practices at Texas Allergy and Breathing Centers in Dallas, Tex. Sarah Allen is a clinical instructor in the PA program at LSUHSC and Emily Weidman-Evans is a clinical professor in the PA program at LSUHSC. The authors have disclosed no potential conflicts of interest, financial or otherwise.

JAAPA : Official Journal of the American Academy of Physician Assistants
|December 28, 2019
PubMed
Summary

Bariatric surgery can improve type 2 diabetes control in obese patients who do not respond to other treatments. Procedures like gastric bypass and sleeve gastrectomy help manage blood glucose and reduce medication needs.

More Related Videos

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

935
A Murine Model of Vertical Sleeve Gastrectomy
06:47

A Murine Model of Vertical Sleeve Gastrectomy

Published on: December 18, 2017

11.6K

Related Experiment Videos

Last Updated: Jan 1, 2026

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

7.2K
Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

935
A Murine Model of Vertical Sleeve Gastrectomy
06:47

A Murine Model of Vertical Sleeve Gastrectomy

Published on: December 18, 2017

11.6K

Area of Science:

  • Endocrinology
  • Metabolic Disorders
  • Surgical Interventions

Background:

  • Type 2 diabetes management typically involves lifestyle changes, self-monitoring, and medication.
  • Maintaining A1C below 7% is crucial for preventing organ damage.
  • Obese patients with uncontrolled diabetes may be candidates for bariatric surgery.

Purpose of the Study:

  • To describe bariatric surgery types for type 2 diabetes.
  • To outline candidate selection, patient education, and postoperative care.
  • To highlight long-term blood glucose control improvements.

Main Methods:

  • Review of bariatric surgical procedures (Roux-en-Y gastric bypass, laparoscopic sleeve gastrectomy).
  • Criteria for selecting surgical candidates with type 2 diabetes.
  • Components of pre- and post-operative patient management.

Main Results:

  • Bariatric surgery improves A1C levels and reduces weight.
  • Patients often require fewer diabetes medications post-surgery.
  • Associated comorbidities like hyperlipidemia and hypertension may also improve.

Conclusions:

  • Bariatric surgery is an effective option for select obese patients with type 2 diabetes.
  • Comprehensive patient management is key to sustained glycemic control.
  • Surgical interventions offer significant benefits beyond glucose management.