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Potent opioids and implications for national defense
1Medical College of Wisconsin, United States.
Toxicology Letters
|December 28, 2019
Summary
Potent opioids like fentanyl are a growing cause of death globally. First responders face risks from accidental exposure and potential weaponization, necessitating preparedness for protection and treatment.
Area of Science:
- Toxicology
- Emergency Medicine
- Public Health
Background:
- Potent opioids, particularly fentanyl and its derivatives, are a significant cause of morbidity and mortality in Western countries.
- These substances are increasingly used as adulterants or substitutes in the illicit drug market across North America and Europe.
- The evolving nature of trafficking and distribution poses challenges in characterizing these chemicals.
Purpose of the Study:
- To highlight the increasing prevalence and risks associated with potent opioids.
- To address the concerns of rescue and emergency personnel regarding unintentional environmental exposures.
- To discuss the potential offensive use of opioid agonists as incapacitating agents.
Main Methods:
- Review of current literature on opioid prevalence and adulteration.
- Analysis of risks to emergency personnel from environmental exposure.
- Examination of evidence regarding the offensive use of opioid agonists.
Main Results:
- Fentanyl and its analogues are widespread in the illicit drug supply.
- Emergency responders are at risk of unintentional exposure during operations.
- There is evidence of opioid agonists being used as incapacitating agents.
Conclusions:
- A comprehensive strategy for protection, decontamination, and treatment is crucial.
- Preparedness is essential for mitigating the risks of potent opioid exposure.
- Understanding the evolving threat landscape is vital for public safety.
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