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Essential Minerals for Bone Health

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

The Bone Matrix

The Bone Matrix

Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...

Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

Bone Disorders

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

Bone Structure

Bone Structure

Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.

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Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

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Published on: February 23, 2024

Natural Medicinal Compounds in Bone Tissue Engineering.

Susmita Bose¹, Naboneeta Sarkar¹

¹W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.

Trends in Biotechnology

|December 29, 2019

Summary

This summary is machine-generated.

3D printing offers advanced solutions for bone defects using patient-specific implants. Incorporating natural medicinal compounds (NMCs) enhances bone regeneration, providing a safe and effective alternative for orthopedic and dental applications.

Keywords:

3D printing bone graft substitutes bone tissue engineering drug delivery natural medicinal compounds

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Published on: November 16, 2018

Area of Science:

Biomaterials Science
Regenerative Medicine
Orthopedics

Background:

3D printing enables patient-specific implants for bone defects.
Natural medicinal compounds (NMCs) possess osteogenic potential.
NMCs offer a safe, effective alternative to synthetic drugs for bone disorders.

Purpose of the Study:

Review challenges in bone tissue engineering.
Highlight the potential of NMCs in 3D-printed scaffolds.
Explore orthopedic and dental applications of NMCs.

Main Methods:

Literature review of recent advances in 3D printing for bone tissue engineering.
Analysis of osteogenic properties of NMCs.
Discussion of NMC integration in 3D-printed scaffolds.

Main Results:

3D printing facilitates complex, patient-specific bone implants.
NMCs can be incorporated into scaffolds to improve bone formation.
NMCs show promise for enhanced implant performance.

Conclusions:

NMCs integrated into 3D-printed scaffolds represent a promising strategy for bone tissue engineering.
This approach offers enhanced bone regeneration for orthopedic and dental applications.
NMCs provide a safe and effective option for treating bone-related disorders.