Polyamine oxidase activity in serum of cancer patients and healthy subjects

Polyamine oxidase (PAO) activity was determined in the serum of cancer patients and healthy subjects. However, the data obtained showed that PAO activity was extremely low or undetectable in the serum of cancer patients and healthy subjects. The difference in PAO activity observed between the sera of cancer patients and healthy subjects was statistically insignificant. Thus, the measurement of PAO activity in serum has no value as a cancer marker.