Related Experiment Video
Updated: Jan 1, 2026

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Published on: August 16, 2017
ShinyGO: a graphical gene-set enrichment tool for animals and plants
Steven Xijin Ge1, Dongmin Jung1,2, Runan Yao1
1Department of Mathematics and Statistics, Brookings, SD 57007, USA.
Motivation:
Gene lists are routinely produced from various omic studies. Enrichment analysis can link these gene lists with underlying molecular pathways and functional categories such as gene ontology (GO) and other databases.
Results:
To complement existing tools, we developed ShinyGO based on a large annotation database derived from Ensembl and STRING-db for 59 plant, 256 animal, 115 archeal and 1678 bacterial species. ShinyGO's novel features include graphical visualization of enrichment results and gene characteristics, and application program interface access to KEGG and STRING for the retrieval of pathway diagrams and protein-protein interaction networks. ShinyGO is an intuitive, graphical web application that can help researchers gain actionable insights from gene-sets.
Availability And Implementation:
http://ge-lab.org/go/.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
Related Concept Videos
Genome Annotation and Assembly
Evolutionary Relationships through Genome Comparisons
Multi-species Conserved Sequences
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Export of Mitochondrial and Chloroplast Genes
Genomics

