Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vision01:24

Vision

59.1K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
59.1K
Visual System01:26

Visual System

1.6K
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
1.6K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

6.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
6.6K
Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

1.7K
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
1.7K
Prosopagnosia01:24

Prosopagnosia

628
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
628
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multinational randomized clinical trial of an eye-tracking-based binocular amblyopia treatment in children aged 4-9 years.

Scientific reports·2026
Same author

Histological findings after subretinal implantation of the PRIMA photovoltaic array in patients with geographic atrophy due to AMD.

Ophthalmology. Retina·2026
Same author

Residual photoreceptors affect the response of a degenerate retina to electrical stimulation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Maximizing the fidelity of a photovoltaic subretinal prosthesis for human patients.

Journal of neural engineering·2026
Same author

Enhancing retinal photoreceptor neurite outgrowth with small molecules and growth factors.

Experimental eye research·2026
Same author

Simulation of prosthetic vision with the PRIMA system and enhancement of face representation.

Journal of neuroengineering and rehabilitation·2026

Related Experiment Video

Updated: Jan 1, 2026

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.1K

Cortical Interactions between Prosthetic and Natural Vision.

Tamar Arens-Arad1, Nairouz Farah1, Rivkah Lender1

  • 1Faculty of Life Sciences, School of Optometry and Vision Science, Bar-Ilan University, Max ve-Anna Webb St, Ramat Gan 5290002, Israel; Bar-Ilan Institute for Nanotechnology and Advanced Materials (BINA), Bar-Ilan University, Max ve-Anna Webb St, Ramat Gan 5290002, Israel.

Current Biology : CB
|December 30, 2019
PubMed
Summary

Researchers studied how the brain combines artificial and natural vision in rats with retinal implants. They found similar visual processing, suggesting potential for restoring sight in age-related macular degeneration (AMD) patients.

More Related Videos

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

805
A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
06:58

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

10.1K

Related Experiment Videos

Last Updated: Jan 1, 2026

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.1K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

805
A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
06:58

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

10.1K

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Biomedical Engineering

Background:

  • Outer retinal degenerative diseases like retinitis pigmentosa and age-related macular degeneration cause incurable blindness.
  • Retinal prostheses can restore vision by stimulating remaining retinal neurons.
  • Age-related macular degeneration affects central vision, leaving peripheral vision intact, creating a unique scenario for combined prosthetic and natural vision.

Purpose of the Study:

  • To investigate cortical interactions between prosthetic and natural vision.
  • To determine if the visual cortex processes combined visual stimuli similarly to natural stimuli.
  • To assess the potential for combined vision restoration in age-related macular degeneration patients.

Main Methods:

  • Utilized a rat model implanted with photovoltaic subretinal implants.
  • Recorded visually evoked potentials (VEPs) to analyze cortical responses.
  • Combined prosthetic and natural vision information within the visual cortex.

Main Results:

  • Observed striking similarities in the interactions of natural and prosthetic vision.
  • Demonstrated similar effects of background illumination on both vision types.
  • Showcased linear summation of non-patterned stimuli and lateral inhibition with spatial patterns, increasing with target contrast.

Conclusions:

  • The visual cortex processes combined natural and prosthetic vision similarly.
  • Findings support the feasibility of combining prosthetic and natural vision for sight restoration in age-related macular degeneration.
  • This research offers hope for improving vision restoration strategies for blindness caused by retinal diseases.