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Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Cameron S Field1, Francesc Baixauli1, Ryan L Kyle1

  • 1Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany.

Cell Metabolism
|December 30, 2019
PubMed
Abstract

Keywords:
FABP5IL-10TregcGAS-STINGimmunometabolismlipidsmtDNAsuppressiontumortype I IFNFatty Acid Binding Protein 5T regulatory cell functionMitochondrial metabolismImmunosuppression in tumors

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