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Updated: Jan 1, 2026
Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
Published on: April 11, 2018
Predicting the knee adduction moment after high tibial osteotomy in patients with medial knee osteoarthritis using
Cynthia Fantini Pagani1, Johannes Funken1, Kai Heinrich1
1Institute of Biomechanics and Orthopaedics, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany.
Background:
High tibial osteotomy (HTO) is a surgical treatment for knee osteoarthritis, which alters the load distribution in the tibiofemoral joint. To date, all surgical planning methods are based on radiographs, which do not consider the loading characteristics during ambulation. This study aimed to develop and validate a simulation tool for predicting the knee adduction moment (KAM) expected after a HTO using the patient pre-operative gait analysis data and dynamic simulations.
Methods:
Ten patients selected for a HTO underwent a gait analysis before surgery. Pre-operative gait data along with the planned correction angle were used for simulation of the KAM expected after leg realignment. After surgery, the same procedures of gait analysis were performed and post-operative KAM was compared to the simulation results.
Results:
Significant reductions of the KAM were observed after surgery. During gait at 1.2 m/s, means of the 1st peak KAM were 3.19 ± 1.03 (standard deviation), 1.21 ± 0.80 and 1.21 ± 0.71% BW × Ht for the conditions pre-operative, post-operative and simulation, respectively. Mean root-mean-square error for the KAM was 0.45% BW × Ht (range: 0.23-0.78% BW × Ht) and Lin's concordance coefficient for the 1st peak KAM was 0.813. An individual analysis showed high agreement for several patients and lower agreement for others. Possible changes in gait pattern after surgery may explain this variability.
Conclusion:
A novel approach for surgical planning based on dynamic loading of the knee during ambulation is presented. The simulation tool is based on patient-specific gait characteristics and may improve the surgical planning procedures used to date.
