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Endoscopic transnasal orbital decompression for Graves.
N Tsetsos1, D Daskalakis2, D Tzakri3
1Department of Otorhinolaryngology-Head and Neck Surgery, 424 General Military Hospital, Thessaloniki, Greece.
Rhinology
|December 30, 2019
Summary
Endoscopic transnasal orbital decompression effectively reduces proptosis in Graves' ophthalmopathy. This systematic review confirms its safety and efficacy for managing this condition.
Area of Science:
- Ophthalmology
- Otorhinolaryngology
- Endocrinology
Background:
- Graves' ophthalmopathy is an autoimmune condition affecting the eye socket.
- Orbital decompression is a surgical option to alleviate symptoms.
Purpose of the Study:
- To systematically review the efficacy of endoscopic transnasal orbital decompression for Graves' ophthalmopathy.
Main Methods:
- Comprehensive literature search of MEDLINE, ScienceDirect, and Cochrane Library.
- Inclusion of twelve prospective and retrospective case series.
- Primary outcome: reduction in orbital proptosis; secondary outcomes: visual acuity, diplopia, complications.
Main Results:
- All studies showed improvement in proptosis (2.07-8.2 mm, mean 5.05 mm).
- Visual acuity improved in most cases.
- Variable results for diplopia; complications included 3 cases of cerebrospinal fluid leak.
Conclusions:
- Endoscopic transnasal decompression is a safe and effective treatment for Graves' ophthalmopathy symptoms.
- Further high-quality, large-sample, controlled studies are recommended.
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