[Сhanges in quality of life in patients with congestive heart failure after cardiac resynchronization therapy]

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Updated: Jan 1, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.9K

G S Pushkarev1, V A Kuznetsov1, Ya A Fisher1

  • 1Tomsk National Research Medical Center, Russian Academy of Sciences, Tyumen Cardiology Research Center.

Kardiologiia
|December 31, 2019
PubMed

Insights

Cardiac resynchronization therapy (CRT) significantly improved physical functioning in congestive heart failure (CHF) patients one year post-procedure. Responders showed overall quality of life (QoL) gains, while non-responders experienced a trend of decline in role-emotional aspects.

Area of Science:

  • Cardiology
  • Medical Devices
  • Quality of Life Research

Background:

  • Congestive heart failure (CHF) significantly impacts patient quality of life (QoL).
  • Cardiac resynchronization therapy (CRT) is a treatment option for select CHF patients.
  • Assessing long-term QoL changes after CRT is crucial for patient management.

Purpose of the Study:

  • To evaluate the changes in QoL among patients with CHF one year after undergoing CRT.
  • To compare QoL outcomes between patients who responded positively to CRT and those who did not.

Main Methods:

  • The study involved 82 CHF patients (mean age 55.8 years) who received biventricular pacemakers for CRT.
  • Patients were categorized into responders (n=56) and non-responders (n=26) based on echocardiographic response.
  • Quality of life was measured using the SF-36 questionnaire before and one year after CRT, assessing eight subscales.

Main Results:

  • A significant improvement in physical functioning (PF) QoL was observed one year post-CRT (p=0.023).
  • Responders showed significant QoL improvements in PF, vitality (VT), and social functioning (SF).
  • Non-responders exhibited a tendency towards decreased role-emotional (RE) QoL (p=0.07).

Conclusions:

  • CRT leads to significant improvements in physical functioning for CHF patients one year after implantation.
  • CRT generally enhances QoL in CRT responders, whereas non-responders may experience a decline in certain QoL aspects.
Abstract

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