Related Experiment Video

Updated: Jan 1, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

14.3K

Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and

Clayton B Woodcock1, Dan Yu1, Taraneh Hajian2

  • 11Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX USA.

Cell Discovery
|December 31, 2019
PubMed
Abstract

No abstract available in PubMed .

Keywords:
MethylationNucleosomes

More Related Videos

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments
09:14

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments

Published on: January 27, 2016

20.0K
Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
06:07

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

2.9K

Related Experiment Videos

Last Updated: Jan 1, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

14.3K
DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments
09:14

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments

Published on: January 27, 2016

20.0K
Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
06:07

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

2.9K

Related Concept Videos

Mismatch Repair01:36

Mismatch Repair

43.4K
Overview
43.4K
Mismatch Repair01:20

Mismatch Repair

6.2K
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
6.2K

Articles linked to this work by shared authors, journal, and citation graph.

Cold-adapted RNA polymerase from Pseudomonas phage Njord improves synthesis of therapeutic mRNA.

Proceedings of the National Academy of Sciences of the United States of America·2026

Coronavirus NSP14 drives internal m7G modification to rewire host splicing and promote viral replication.

Nucleic acids research·2026

Semirandom DNA adducts regulate a filamentous defense-associated reverse transcriptase.

Nature structural & molecular biology·2026

Systematic screening of archaeal MazF homologs reveals Tth-MazF1, a versatile, sequence-specific ribonuclease from Thermococcus thioreducens.

Nucleic acids research·2026

Type II Restriction of 2-Aminoadenosine (dZ)-Modified DNA and Production of dZ-Modified Plasmid in E. coli.

Viruses·2026

OLD amputates the anticodon arm of tRNAs during P2-Lambda interference.

Nucleic acids research·2025

Structural insights into the ligand modulation of MRGPRX4 conformational plasticity.

Cell discovery·2026

Blocking PD1 prevents T-cell-promoted fibrosis in myocardial infarction.

Cell discovery·2026

Structural basis of the transport mechanism of hBGT1.

Cell discovery·2026

Eggerthella lenta disrupts the gut vascular barrier to drive colorectal cancer liver metastasis.

Cell discovery·2026

The accessory protein ORF3a hijacks the CLCC1 chloride channel to disrupt ER homeostasis in betacoronavirus pathogenesis.

Cell discovery·2026

HMMR+ stromal cells drive human uterine development.

Cell discovery·2026

Preoperative CT Suspicion of Main Pancreatic Duct Injury in Isolated Blunt Pancreatic Trauma: A Case Report With Operative Correlation.

Clinical case reports·2026

An unusual phenomenon observed during quantitative 1H NMR analysis using 1,3,5-trimethoxybenzene as internal standard: H/D exchange of the internal standard in deuterated solvents under acidic conditions.

Journal of pharmaceutical and biomedical analysis·2026

Characterization of flavor profiles and key discriminant compounds in citrus essential oils via metabolomics combined with sensory analysis.

Food chemistry·2026

Data fusion of high-performance liquid chromatography and near-infrared spectroscopy with explainable machine learning for commercial origin authentication of Cimicifugae Rhizoma.

Journal of chromatography. A·2026

Single-step Raman spectroscopy for maple syrup quality control.

RSC advances·2026

ZnO/ZIF-8@Au nanoarchitectures with nanoconfinement-enhanced plasmonic coupling for ultrasensitive photoelectrochemical detection of malondialdehyde.

Analytica chimica acta·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us