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Updated: Aug 8, 2026

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
Published on: April 23, 2015
[A computer ethological-pharmacological analysis of the intraspecific behavior of primates]
Abstract:
Experiments were performed on primates (Cercopithecus sabeus, Macaca maurus, Cebus apella). Possibility to formalize the structure of normal and pathological monkey behaviour was shown by computerized technique. Rigid dominant-subordinate structures (linear type) were demonstrated on Macaca maurus, Cercopithecus sabeus, Cebus apella. These structures display some variants of normal relationship between monkeys. Raising in isolation from conspecifics determines behavioural disadaptation and pathological behaviour, e.g. "timid-defensive" syndrome. Model of "timid-defensive" syndrome in isolated primates seems to be useful for psycho-pharmacological research, for assessment of anxiolytic and antidepressive properties of drugs.
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