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In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
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Highly Stable, Functional Hairy Nanoparticles and Biopolymers from Wood Fibers: Towards Sustainable Nanotechnology
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Oxidized cellulose-based hemostatic materials.

Shaohua Zhang1, Jiwei Li2, Shaojuan Chen2

  • 1Department of Pediatrics, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.

Carbohydrate Polymers
|January 1, 2020
PubMed
Summary
This summary is machine-generated.

Oxidized cellulose is a key biodegradable hemostatic agent for surgery. This review comprehensively assesses its preparation, mechanisms, forms, and products, highlighting recent advancements in oxidized cellulose hemostatic materials.

Keywords:
Antibacterial activityBiodegradabilityHemostatic materialsOxidized cellulose

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Area of Science:

  • Biomaterials Science
  • Surgical Innovation
  • Hemostasis Research

Background:

  • Hemostatic agents are critical for managing surgical bleeding and preventing mortality.
  • Oxidized cellulose, a biodegradable and biocompatible material, is widely used in surgery.
  • A comprehensive review of oxidized cellulose-based hemostatic materials is lacking.

Purpose of the Study:

  • To provide a thorough review of oxidized cellulose-based hemostatic materials.
  • To cover preparation, properties, mechanisms, and commercial products.
  • To highlight recent scientific developments in the field.

Main Methods:

  • Literature review of scientific publications.
  • Analysis of oxidized cellulose preparation and properties.
  • Synthesis of information on hemostatic mechanisms, forms, modifications, and products.

Main Results:

  • Detailed review of oxidized cellulose preparation, origin, structure, biodegradability, and safety.
  • Comprehensive discussion of hemostatic mechanisms, various forms, and modifications.
  • Overview of currently available commercial oxidized cellulose hemostatic products.

Conclusions:

  • This paper summarizes the latest advancements in oxidized cellulose hemostatic materials.
  • It serves as a valuable reference for future research and development in this area.
  • Oxidized cellulose remains a significant material in surgical hemostasis.