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Ischemic Heart Disease: Overview01:17

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Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
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Updated: Dec 31, 2025

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Ischemic stroke in Morocco: a systematic review.

Ahmed Kharbach1, Majdouline Obtel2,3, Laila Lahlou3,4

  • 1Laboratory of Biostatistics, Clinical Research and Epidemiology (LBRCE), Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, 10100, Rabat, Morocco. kharbach.a.lbrce@gmail.com.

BMC Neurology
|January 1, 2020
PubMed
Summary

Ischemic stroke disproportionately affects younger males in Morocco, with significant prehospital delays and low thrombolysis rates. Further research is needed to improve patient access to care and stroke management.

Keywords:
Ischemic strokeMoroccoPrehospital delayThrombolysisTrial of ORG classification 10,172 in acute stroke treatment classification

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Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Ischemic stroke presents unique epidemiological and etiological challenges in Morocco.
  • Understanding prehospital delay, thrombolysis rates, and mortality is crucial for improving stroke care.
  • Genetic factors in Moroccan ischemic stroke patients require further investigation.

Purpose of the Study:

  • To systematically review the epidemiological and etiological profiles of ischemic stroke in Morocco.
  • To identify factors influencing prehospital delay and thrombolysis management.
  • To determine acute and 3-month mortality rates and explore genetic aspects.

Main Methods:

  • Systematic review adhering to PRISMA guidelines.
  • Searched PubMed, ScienceDirect, Scopus, ClinicalKey, and Google Scholar (2009-2018).
  • Analyzed data on demographics, risk factors, etiology, prehospital delay, thrombolysis, mortality, and genetics.

Main Results:

  • Included 29 studies with average patient ages from 49 to 67.3 years; male predominance observed.
  • Key risk factors: hypertension, diabetes, smoking, heart disease. Main etiologies: atherosclerosis, cardioembolism.
  • Average prehospital delay: 26-61.9 hours; thrombolysis rate: 1.8-2.9%; mortality: 3-13% (acute), 4.3-32.5% (3-month).

Conclusions:

  • Ischemic stroke impacts younger populations, with a notable male predominance in Morocco.
  • Alarmingly long prehospital delays and low thrombolysis rates necessitate urgent attention.
  • Investigating factors affecting access to care is essential for enhancing stroke management in Morocco.