Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

3.4K
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The enduring pursuit of science in America.

Science (New York, N.Y.)·2026
Same author

The undulating tripod gait as a model of the locomotion of walking fish.

Nature communications·2026
Same author

Large multicenter validation of urine RNA profile for urothelial carcinoma detection and surveillance.

The Journal of clinical investigation·2026
Same author

Co-option of an ancestral cloacal regulatory landscape during digit evolution.

Nature·2025
Same author

Whole tissue imaging of cellular boundaries at sub-micron resolutions for deep learning cell segmentation: Applications in the analysis of epithelial bending of ectoderm.

Developmental dynamics : an official publication of the American Association of Anatomists·2025
Same author

The origin of vertebrate teeth and evolution of sensory exoskeletons.

Nature·2025

Related Experiment Video

Updated: Dec 31, 2025

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging
06:20

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging

Published on: April 28, 2022

2.4K

Fin ray patterns at the fin-to-limb transition.

Thomas A Stewart1, Justin B Lemberg2, Natalia K Taft3

  • 1Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637; tomstewart@uchicago.edu nshubin@uchicago.edu.

Proceedings of the National Academy of Sciences of the United States of America
|January 1, 2020
PubMed
Summary

The study reveals that dermal fin rays in early tetrapodomorphs evolved asymmetry and consolidation, adapting fins for weight-bearing and substrate interaction before digits emerged. This research highlights fin ray evolution during the fin-to-limb transition.

Keywords:
dermal skeletonevolutionfin-to-limb transitionpaleontology

More Related Videos

In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin
07:22

In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin

Published on: March 29, 2012

17.4K
Capturing Tissue Repair in Zebrafish Larvae with Time-lapse Brightfield Stereomicroscopy
14:29

Capturing Tissue Repair in Zebrafish Larvae with Time-lapse Brightfield Stereomicroscopy

Published on: January 31, 2015

11.4K

Related Experiment Videos

Last Updated: Dec 31, 2025

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging
06:20

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging

Published on: April 28, 2022

2.4K
In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin
07:22

In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin

Published on: March 29, 2012

17.4K
Capturing Tissue Repair in Zebrafish Larvae with Time-lapse Brightfield Stereomicroscopy
14:29

Capturing Tissue Repair in Zebrafish Larvae with Time-lapse Brightfield Stereomicroscopy

Published on: January 31, 2015

11.4K

Area of Science:

  • Paleontology
  • Evolutionary Biology
  • Comparative Anatomy

Background:

  • The fin-to-limb transition involved digit origin and dermal fin ray loss.
  • Research has primarily focused on endoskeleton evolution, neglecting fin ray structure and function.

Purpose of the Study:

  • Investigate dermal ray structure and function in key tetrapodomorph taxa.
  • Identify evolutionary trends in fin rays leading to tetrapods.

Main Methods:

  • Computed tomography (CT) scanning of pectoral fin dermal rays.
  • Analysis of three taxa: Sauripterus taylori, Eusthenopteron foordi, and Tiktaalik roseae.
  • Comparative analysis with extant osteichthyans.

Main Results:

  • Observed consolidation of fin rays (reduced segmentation/branching) and fin web reduction.
  • Documented evolution of asymmetry between dorsal and ventral hemitrichia (fin rays).
  • Tiktaalik roseae showed significant dorsal ray enlargement and ventral restriction, suggesting specialized fin-tip musculature.

Conclusions:

  • Dermal ray asymmetry in paired fins is likely a plesiomorphic trait in Osteichthyes.
  • Evolving fin ray structures in stem tetrapods indicate adaptations for elevated posture and substrate loading.
  • These fin ray adaptations preceded the origin of digits, playing a crucial role in tetrapod evolution.