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Updated: Dec 31, 2025
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Computed tomography-guided cryoablation for functional adrenal aldosteronoma
Yu-Fei Fu1, Chi Cao1, Yi-Bing Shi1
1Department of Radiology, Xuzhou central hospital, Xuzhou, China.
Purpose:
To assess the safety and clinical effectiveness of computed tomography (CT)-guided cryoablation for functional adrenal aldosteronoma.
Material And Methods:
From June 2012 to December 2018, 11 patients with functional adrenal aldosteronoma underwent CT-guided cryoablation in our center. Data comprising complete ablation rate, clinical success rate, procedure-related complications and long-term outcome were collected and analyzed.
Results:
A total of 11 aldosteronoma in 11 patients were treated. Complete ablation was achieved in all patients after a single ablation session. No procedure-related complications occurred. Clinical success rate was 100%. Mean aldosterone levels, and systolic and diastolic pressure decreased from 858.6 ± 93.2 pmol/L, 156.4 ± 7.8 mmHg and 90.0 ± 10.5 mmHg prior to treatment, respectively, to 321.8 ± 41.2 pmol/L (p < .001), 129.1 ± 9.4 mmHg (p < .001) and 76.4 ± 5.5 mmHg (p = .005) after treatment, respectively. Mean renin and potassium improved from 0.2 ± 0.1 μg/L/h and 2.9 ± 0.2 mmol/L before treatment, respectively to 4.6 ± 0.4 μg/L/h (p < .001) and 4.2 ± 0.2 mmol/L (p < .001) following treatment, respectively. No tumor or clinical symptom recurrence occurred during the follow-up.
Conclusions:
CT-guided cryoablation is a safe and effective method for the treatment of functional adrenal aldosteronoma.
