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Updated: Dec 31, 2025

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
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Addressing hERG activity while maintaining favorable potency, selectivity and pharmacokinetic properties of PPARδ

Bharat Lagu1, Ramesh S Senaiar2, Arthur F Kluge1

  • 1Mitobridge, Inc. (a wholly owned subsidiary of Astellas Pharma.), 1030 Massachusetts Avenue, Cambridge, MA 02138, USA.

Bioorganic & Medicinal Chemistry Letters
|January 1, 2020
PubMed

Keywords:
PPARδ modulatorsPatch clamp assayTPSAcLogPhERGpKa

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