Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

39.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.5K
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

52.0K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
52.0K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

15.2K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.2K
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

48.0K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
48.0K
Genetic Material01:20

Genetic Material

3.1K
Within the human body, a complex and detailed system of trillions of cells works in unison to sustain life. Each cell houses a nucleus, which contains 46 chromosomes divided into 23 pairs. Chromosomes are highly coiled structures made of the genetic material DNA. These chromosomes are essential carriers of genetic information, with half inherited from the mother through her egg and the other half from the father's sperm, combining to create the unique genetic makeup of an individual.
3.1K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

6.1K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"It didn't feel like anything unusual because we had already been through so much": Disability-Related Research Experiences of Families with Children Enrolled in the Undiagnosed Diseases Network.

Genetics in medicine : official journal of the American College of Medical Genetics·2026
Same author

The relationship between resilience, identity, and perceived stress among Indigenous students at a large southwestern university.

Journal of American college health : J of ACH·2026
Same author

Pharmacotherapy for alcohol misuse: Views of patients, providers, and leaders in an Alaska Native healthcare system.

Journal of substance use and addiction treatment·2026
Same author

The Mental Health Impacts of the COVID-19 Pandemic on Adults With Intellectual and Developmental Disabilities: A Qualitative Study.

Journal of applied research in intellectual disabilities : JARID·2026
Same author

Forced resilience: Indigenous perspectives on systemic barriers and humanizing genomic medicine in British Columbia, Canada.

Genetics in medicine : official journal of the American College of Medical Genetics·2026
Same author

Positive childhood experiences and mental health among Indigenous peoples: A scoping review.

Psychological trauma : theory, research, practice and policy·2026

Related Experiment Video

Updated: Dec 31, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.7K

Access and Management: Indigenous Perspectives on Genomic Data Sharing.

Nanibaa' A Garrison1,2, Krysta S Barton1, Kathryn M Porter1

  • 1Treuman Katz Center for Pediatric Bioethics, Seattle Children's Hospital and Research Institute, Seattle, WA.

Ethnicity & Disease
|January 1, 2020
PubMed
Summary

Tribal leaders seek greater control over genetic research and data sharing, emphasizing ownership and ethical considerations for American Indian/Alaska Native/Native Hawaiian communities. Findings will inform policies for tribal-driven, culturally appropriate research.

Keywords:
Genomic Data SharingTribal Sovereignty

More Related Videos

Microbial Communities in Nature and Laboratory - Interview
29:13

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

6.7K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

34.5K

Related Experiment Videos

Last Updated: Dec 31, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.7K
Microbial Communities in Nature and Laboratory - Interview
29:13

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

6.7K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

34.5K

Area of Science:

  • Genomics
  • Bioethics
  • Indigenous Studies

Background:

  • Genomic research is expanding, necessitating broad data sharing.
  • American Indian/Alaska Native/Native Hawaiian (AI/AN/NH) leaders express concerns regarding data ownership, biospecimens, and tribal sovereignty.
  • Ethical considerations are paramount for AI/AN/NH communities in genetic research.

Purpose of the Study:

  • To explore perspectives of AI/AN/NH tribal leaders, clinicians, researchers, policymakers, and tribal research review board members on ethical issues in genetics.
  • To understand community views on genetic research and data sharing models.
  • To identify needs for stronger oversight and management of genetic data.

Main Methods:

  • Community-engaged research approach.
  • Conducted 42 semi-structured interviews with diverse stakeholders.
  • Gathered insights on perspectives of genetic research, data sharing, and data governance.

Main Results:

  • Participants raised concerns about various data sharing models and infrastructure for data housing.
  • Questions arose regarding the authority to grant access to genetic data.
  • A strong desire for tribal oversight and management of data was evident.

Conclusions:

  • Findings highlight the need for policies and guidelines that empower tribes to lead research agendas.
  • Ethically and culturally appropriate research practices are crucial for AI/AN/NH communities.
  • Strengthening tribal data governance is essential for responsible genomic research.