Saliva proteomics updates in biomedicine
Katerina R Katsani1, Dimitra Sakellari2
11Department of Molecular Biology & Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Journal of Biological Research (Thessalonike, Greece)
|January 1, 2020
Summary
This review highlights advances in saliva proteomics, a key
Area of Science:
- Biomedical Sciences
- Biomarker Discovery
- Proteomics and Metabolomics
Background:
- Personalized medicine utilizes 'omics' methodologies (genomics, transcriptomics, proteomics, metabolomics) for biomarker detection.
- Proteomics employs high-throughput, bioinformatic-supported approaches to identify and quantify proteins.
- Saliva is a practical biological specimen for health monitoring, offering advantages over blood.
Purpose of the Study:
- To review the latest advancements in saliva proteomics.
- To emphasize the role of saliva proteomics in biomedicine.
Main Methods:
- Review of current literature on saliva proteomics.
- Analysis of high-throughput and bioinformatic tools in proteomics.
- Evaluation of saliva as a biological fluid for health monitoring.
Main Results:
- Saliva proteomics is rapidly advancing.
- Proteomic analysis of saliva offers practical advantages for health monitoring.
- Latest techniques enable comprehensive protein profiling in saliva.
Conclusions:
- Saliva proteomics holds significant promise for personalized medicine.
- Continued research in saliva proteomics will enhance disease diagnosis and monitoring.
- The review underscores the potential of saliva as a diagnostic fluid.
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