Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Redox Equilibria: Overview01:23

Redox Equilibria: Overview

1.5K
A reduction-oxidation reaction is commonly called a redox reaction. In a redox reaction, electrons are transferred from one species to another rather than being shared between or among atoms. The reducing agent or reductant is the species that loses electrons and gets oxidized in the process. The species that gains electrons and gets reduced in the process is the oxidizing agent or oxidant. Redox reactions are represented as two separate equations called half-reactions, where one equation...
1.5K
Redox Reactions01:27

Redox Reactions

791
Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
791
Redox Reactions01:24

Redox Reactions

58.1K
Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
58.1K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

74.7K
Oxidation–Reduction Reactions
74.7K
Ladder Diagrams: Redox Equilibria01:30

Ladder Diagrams: Redox Equilibria

713
Ladder diagrams are useful tools for understanding redox equilibrium reactions, especially the effects of concentration changes on the electrochemical potential of the reaction. The vertical axis in the redox ladder diagrams represents the electrochemical potential, E. The area of predominance is demarcated using the Nernst equation.
Consider the Fe3+/Fe2+ half-reaction, which has a standard-state potential of +0.771 V. At potentials more positive than +0.771 V, Fe3+ predominates, whereas Fe2+...
713
Balancing Redox Equations02:58

Balancing Redox Equations

61.1K
Electrochemistry is the science involved in the interconversion of electrical and chemical reactions. Such reactions are called reduction-oxidation, or redox reactions. These important reactions are defined by changes in oxidation states for one or more reactant elements and include a subset of reactions involving the transfer of electrons between reactant species. Electrochemistry as a field has evolved to yield sufficient insights on the fundamental principles of redox chemistry and multiple...
61.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oral oxycodone versus sublingual buprenorphine for postoperative pain control after pelvic exenteration (PROSPER): a pilot, registry-embedded, multi-centre, double-blind, placebo-controlled, randomised controlled trial.

BMJ open·2026
Same author

Simultaneous robotic-assisted prostatectomy and rectal resection: a systematic review.

Journal of robotic surgery·2025
Same author

Continuous infusion of piperacillin/tazobactam optimizes intraoperative antibiotic exposure in patients undergoing elective pelvic exenteration surgery.

Antimicrobial agents and chemotherapy·2024
Same author

Nutrition-related predictors of complications and length of hospital stay following total pelvic exenteration surgery.

Clinical nutrition ESPEN·2024
Same author

Discovery of a novel series of selective macrocyclic PKCTheta inhibitors.

Bioorganic & medicinal chemistry letters·2024
Same author

Spatiotemporal protein dynamics during early organogenesis in mouse conceptuses treated with valproic acid.

Neurotoxicology and teratology·2023

Related Experiment Video

Updated: Dec 31, 2025

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
10:05

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

2.2K

The Redox Theory of Development.

Jason M Hansen1, Dean P Jones2, Craig Harris3

  • 1Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah.

Antioxidants & Redox Signaling
|January 1, 2020
PubMed
Summary

Oxygen levels influence the evolution of complex organisms and embryonic development. Redox regulation of cysteine proteomes controls key developmental events, with disruptions leading to adverse outcomes.

Keywords:
developmentdifferentiationmetabolismorganogenesisoxygenredox

More Related Videos

Analysis of Oxidative Stress in Zebrafish Embryos
11:05

Analysis of Oxidative Stress in Zebrafish Embryos

Published on: July 7, 2014

38.0K
Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein
06:10

Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein

Published on: June 18, 2020

7.7K

Related Experiment Videos

Last Updated: Dec 31, 2025

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
10:05

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

2.2K
Analysis of Oxidative Stress in Zebrafish Embryos
11:05

Analysis of Oxidative Stress in Zebrafish Embryos

Published on: July 7, 2014

38.0K
Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein
06:10

Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein

Published on: June 18, 2020

7.7K

Area of Science:

  • Evolutionary Biology
  • Developmental Biology
  • Biochemistry

Background:

  • Rising atmospheric oxygen levels correlate with the evolution of complex organisms (metazoans).
  • Higher organisms possess cysteine-rich proteomes for homeostasis in oxygen-rich environments.
  • Oxygen acts as a developmental morphogen, influencing embryonic development through redox-sensitive pathways.

Purpose of the Study:

  • To explore the role of oxygen and redox-sensitive elements in regulating embryonic development.
  • To investigate how oxygen fluctuations reprogram embryos at genomic and metabolic levels.
  • To understand the impact of redox regulation on cysteine proteome modifications and protein function during development.

Main Methods:

  • Analysis of the geological record for correlations between oxygen levels and metazoan evolution.
  • Investigating embryonic reprogramming under varying oxygen conditions.
  • Examining oxidative post-translational modifications (PTMs) of cysteine residues in key developmental processes.

Main Results:

  • Oxygen fluctuations during development trigger genomic and metabolic reprogramming.
  • Redox regulation of cysteine-based redox nodes controls major developmental events like stem cell expansion and differentiation.
  • Proper redox signaling is crucial for normal development and reproduction; disruptions cause adverse outcomes.

Conclusions:

  • Oxygen is a critical regulator of embryonic development, acting as a morphogen.
  • Oxidative PTMs of cysteine proteomes are essential for controlling developmental processes.
  • Understanding redox regulation pathways is key to comprehending developmental disorders and improving reproductive outcomes.