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Updated: Dec 31, 2025

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
Published on: February 19, 2016
A highly sensitive and accurate SERS/RRS dual-spectroscopic immunosensor for clenbuterol based on
Dongmei Yao1, Chongning Li2, Guiqing Wen2
1Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin, 541004, China; College of Chemistry and Biology Engineering, Hechi University, Yizhou, 546300, China.
Abstract:
Preparation of multifunctional codoped carbon dots, and their new analytical applications in surface-enhanced Raman scattering (SERS) quantitative analytical method are still challenge. To overcome these problems, the nitrogen/silver-codoped carbon dots (CDN/Ag) with highly catalytic amplification are prepared by microwave method, and characterized by spectrophotometry and electron microscopy. The results show that CDN/Ag can strongly catalyze trisodium citrate-HAuCl4 reaction to generate red nanogold with resonance Rayleigh scattering (RRS) effect and SERS effect using Victoria blue B (VBB) as molecular probes. The CDN/Ag catalytic amplification and specific immunoreaction of clenbuterol (Clen) are coupled with highly sensitive SERS and accurate RRS to fabricate a new dual-spectroscopic strategy with a detection limit of 0.68 pg mL-1 Clen.

