Chronic mesenteric ischaemia masked by candida esophagitis in a renal transplant patient

Seth Scheetz1, Deepali Pandey2, Todd E Pesavento1

  • 1Comprehensive Transplant Center, Ohio State University, Columbus, Ohio, USA.

BMJ Case Reports
|January 2, 2020
PubMed

Insights

Chronic mesenteric ischemia, often missed due to non-specific symptoms, can be obscured by infections in immunosuppressed patients. This case highlights a superior mesenteric artery thrombus mimicking candida esophagitis, requiring urgent surgical intervention.

Area of Science:

  • Gastroenterology
  • Vascular Surgery
  • Infectious Diseases

Background:

  • Chronic mesenteric ischemia (CMI) presents non-specifically, complicating diagnosis.
  • Immunosuppressed patients are prone to infections that can mimic or mask CMI.
  • Accurate diagnosis of CMI is crucial due to its severe morbidity and mortality.

Observation:

  • A patient presented with symptoms initially suggestive of candida esophagitis.
  • The patient was immunosuppressed, increasing the risk of gastrointestinal infections.
  • Worsening leukocytosis persisted despite initial treatment for presumed infection.

Findings:

  • Re-evaluation revealed a superior mesenteric artery thrombus as the cause of mesenteric ischemia.
  • The clinical presentation mimicked infectious esophagitis, delaying CMI diagnosis.
  • Urgent surgical intervention was necessary for the patient's mesenteric ischemia.

Implications:

  • This case underscores the importance of considering CMI in non-specific abdominal presentations, especially in immunosuppressed individuals.
  • Diagnostic challenges in CMI require a high index of suspicion and thorough investigation.
  • Timely surgical management is critical for favorable outcomes in acute mesenteric ischemia.

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
246
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
282
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
270
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
486
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
691