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Chronic mesenteric ischaemia masked by candida esophagitis in a renal transplant patient
Seth Scheetz1, Deepali Pandey2, Todd E Pesavento1
1Comprehensive Transplant Center, Ohio State University, Columbus, Ohio, USA.
Abstract:
Chronic mesenteric ischaemia is a severe disease that is often missed due to its non-specific presentation. Immunosuppressed patients are at risk for infectious gastrointestinal disease, which may further obscure the diagnosis of chronic mesenteric ischaemia. In this case, a patient's symptoms and diagnostic workup were consistent with candida esophagitis. Worsening leukocytosis despite treatment, however, prompted re-evaluation ultimately revealing a superior mesenteric artery thrombus causing mesenteric ischaemia. The patient required urgent surgical intervention for the management of his disease.
Insights
Chronic mesenteric ischemia, often missed due to non-specific symptoms, can be obscured by infections in immunosuppressed patients. This case highlights a superior mesenteric artery thrombus mimicking candida esophagitis, requiring urgent surgical intervention.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Infectious Diseases
Background:
- Chronic mesenteric ischemia (CMI) presents non-specifically, complicating diagnosis.
- Immunosuppressed patients are prone to infections that can mimic or mask CMI.
- Accurate diagnosis of CMI is crucial due to its severe morbidity and mortality.
Observation:
- A patient presented with symptoms initially suggestive of candida esophagitis.
- The patient was immunosuppressed, increasing the risk of gastrointestinal infections.
- Worsening leukocytosis persisted despite initial treatment for presumed infection.
Findings:
- Re-evaluation revealed a superior mesenteric artery thrombus as the cause of mesenteric ischemia.
- The clinical presentation mimicked infectious esophagitis, delaying CMI diagnosis.
- Urgent surgical intervention was necessary for the patient's mesenteric ischemia.
Implications:
- This case underscores the importance of considering CMI in non-specific abdominal presentations, especially in immunosuppressed individuals.
- Diagnostic challenges in CMI require a high index of suspicion and thorough investigation.
- Timely surgical management is critical for favorable outcomes in acute mesenteric ischemia.
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