Related Experiment Video
Updated: Dec 31, 2025
09:43
Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
3.4K
Systemic lupus erythematosus presenting as Evans syndrome
Liya Stolyar1, Bijan Rizi1, Sonia Lin1
1Department of Internal Medicine University of Southern California Los Angeles California.
Clinical Case Reports
|January 2, 2020
Summary
Systemic lupus erythematosus (SLE) diagnosis can involve hematologic abnormalities. This case highlights Evans Syndrome presenting with underlying SLE at initial diagnosis.
Area of Science:
- Hematology
- Immunology
- Rheumatology
Background:
- Hematologic abnormalities are key diagnostic criteria for systemic lupus erythematosus (SLE).
- Evans Syndrome is a rare autoimmune disorder characterized by autoimmune hemolytic anemia and immune thrombocytopenia.
Observation:
- This case report details a patient initially diagnosed with Evans Syndrome.
- The patient's presentation included significant hematologic abnormalities.
Findings:
- The underlying diagnosis of systemic lupus erythematosus (SLE) was identified at the initial presentation.
- This suggests a potential link between Evans Syndrome and the onset of SLE.
Implications:
- Recognizing hematologic abnormalities is crucial for early SLE diagnosis.
- This case underscores the importance of considering SLE in patients presenting with Evans Syndrome.
Keywords:
SLE Evans thrombocytopenia
Related Concept Videos
01:24Nephrotic Syndrome I : Introduction
430
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
430
01:26Nephrotic Syndrome II : Assessment and Medical Management
161
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
161
01:24Nephrotic Syndrome III : Nursing Management
242
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
242
01:25Endocarditis II: Clinical Features of Infective Endocarditis
316
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
316
01:24Chronic Kidney Disease II: Clinical Manifestations
486
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
486
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
386
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
386