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Metabolic Network Reconstructions to Predict Drug Targets and Off-Target Effects

Kristopher Rawls1, Bonnie V Dougherty1, Jason Papin2

  • 1Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.

Methods in Molecular Biology (Clifton, N.J.)
|January 2, 2020
PubMed

Keywords:
Constraint-based modelingDrug targetsFlux balance analysis (FBA)Genome-scale metabolic network reconstruction (GENRE)Off-target effects

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