Related Experiment Video
Updated: Aug 4, 2026
06:24
Mouse Models of Periventricular Leukomalacia
Published on: May 19, 2010
A mouse malformation mutant supplement to the London Dysmorphology Database
1Clinical Research Centre, Northwick Park Hospital, Harrow, Middlesex, United Kingdom.
American Journal of Medical Genetics
|July 1, 1988
Summary
A new mouse malformation mutant database is available to researchers. This resource allows searching for specific combinations of physical abnormalities in mouse models, aiding genetic research.
Area of Science:
- Developmental Biology
- Genetics
- Bioinformatics
Background:
- The London Dysmorphology Database is a key resource for human genetic disorders.
- Mouse models are crucial for understanding human disease genetics and developmental abnormalities.
Purpose of the Study:
- To describe a new supplementary database focused on mouse malformation mutants.
- To provide a searchable resource for researchers studying genetic causes of physical abnormalities in mice.
Main Methods:
- Development of a microcomputer-based database.
- Implementation of search functionalities for specific combinations of physical abnormalities.
Main Results:
- A functional database of mouse malformation mutants has been created.
- The database enables targeted retrieval of mutants based on phenotypic traits.
Conclusions:
- This database serves as a valuable, free resource for the scientific community.
- Facilitates research into genotype-phenotype correlations in mouse models.
