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Duplication of a small segment of 5p due to maternal recombination within a paracentric shift

G C Webb1, L E Voullaire, J G Rogers

  • 1Department of Genetics, Royal Children's Hospital, Melbourne, Australia.

Duplication of chromosome sub-bands 5p14.3 and 5p15.1 in a child resulted in mild mental retardation, apparently without other abnormalities. The duplicated region arises from recombination within a directly inserted segment following a shift within the short arm of the maternal chromosome 5 homologs.

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