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Updated: Dec 31, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophilic esophagitis: imaging features with endoscopic and pathologic correlation
Patricia V Hernandez1, Syed Amer2, Dora M Lam-Himlin3
1Department of Gastroenterology and Hepatology, Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ, 85259, USA.
Fluoroscopy can reveal key imaging features of eosinophilic esophagitis, correlating with endoscopic and pathologic findings. This aids in diagnosing this chronic immune-mediated esophageal disease.
Area of Science:
- Gastroenterology
- Radiology
- Immunology
Background:
- Eosinophilic esophagitis (EoE) is a chronic immune-mediated esophageal disorder causing dysfunction.
- Diagnosis relies on endoscopic biopsies showing eosinophil-predominant inflammation.
- Esophageal imaging offers insights into structural and functional changes.
Purpose of the Study:
- To review fluoroscopic imaging features of eosinophilic esophagitis.
- To correlate these findings with endoscopic and pathologic results.
- To highlight the role of radiology in assessing EoE.
Main Methods:
- Review of fluoroscopic imaging in patients with eosinophilic esophagitis.
- Correlation of imaging findings with endoscopic and histopathologic data.
- Analysis of structural and functional esophageal changes.
Main Results:
- Fluoroscopy can identify characteristic imaging features of eosinophilic esophagitis.
- Radiologic findings may correlate with endoscopic and pathologic assessments.
- Fluoroscopic studies are valuable for detecting subtle changes and fibrotic remodeling.
Conclusions:
- Radiologic examinations are valuable tools for assessing eosinophilic esophagitis.
- Fluoroscopy can reveal fibrostenotic changes, such as narrowing, more clearly than endoscopy.
- Recognizing radiologic signs facilitates earlier diagnosis and treatment of EoE.
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