NeuroChat with Professor P. Jeffrey Conn

Discovery of VU6081679, a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 8 with Efficacy in a Preclinical Model of Parkinson's Disease.

ACS chemical neuroscience·2026

Optimization of Pyrazole-Based Activators of Kv3.1.

ACS medicinal chemistry letters·2026

Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons.

ACS chemical neuroscience·2026

Discovery of VU6066098: A Selective and CNS-Penetrant mGlu2 NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents.

ACS chemical neuroscience·2026

Discovery of VU6053371/BI03738809: A First-in-Class Selective and CNS-Penetrant mGlu3 Positive Allosteric Modulator (PAM) with Efficacy in a Preclinical Cognition Model.

ACS chemical neuroscience·2026

Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2.

Journal of medicinal chemistry·2026

Role of β-Arrestin2 Signaling in Neuropharmacological Effects of Psychedelic Drugs.

ACS chemical neuroscience·2026

G2019S LRRK2 Kinase Inhibition in Heterozygous Mice Avoids Lung Phenotype Observed with Inhibition of WT LRRK2.

ACS chemical neuroscience·2026

Modulating Stress Granules via HDAC6 Inhibition: A Promising Strategy against Alzheimer's Disease.

ACS chemical neuroscience·2026

Microbes and Microbial Chemical Matter in the Seeding of Alzheimer's Disease: Prospects for Orthogonal Therapies.

ACS chemical neuroscience·2026

Emerging Promise of Sulforaphane in Autism: A Comprehensive Review of Its Therapeutic Potential and Mechanisms.

ACS chemical neuroscience·2026

Development of Aryl Cyano Amides for Fluorescence Discrimination of Tau and Amyloid Beta Deposits in Tissue.

ACS chemical neuroscience·2026

Enhancing spin coherence of an optically addressed molecular qubit by nuclear spin hyperpolarization.

Physical chemistry chemical physics : PCCP·2026

Real-Space Mapping of Emergent Correlated Electronic States With Scanning SQUID Microscopy.

Advanced materials (Deerfield Beach, Fla.)·2026

Testing quantum-like markers in neural dynamics.

Journal of computational neuroscience·2026

Linking Chemical Structure and Coherence Times of Molecular Spin Qubits.

JACS Au·2026

Participation ratio as a quantum probe of hierarchical stickiness.

Chaos (Woodbury, N.Y.)·2026

Hot Electrons Control of Quantum Dot Emission Using Plasmonic Supercells.

The journal of physical chemistry. C, Nanomaterials and interfaces·2026

Related Experiment Videos

NeuroChat with Professor P. Jeffrey Conn

Related Concept Videos

Discovery of VU6081679, a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 8 with Efficacy in a Preclinical Model of Parkinson's Disease.

Optimization of Pyrazole-Based Activators of Kv3.1.

Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons.

Discovery of VU6066098: A Selective and CNS-Penetrant mGlu2 NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents.

Discovery of VU6053371/BI03738809: A First-in-Class Selective and CNS-Penetrant mGlu3 Positive Allosteric Modulator (PAM) with Efficacy in a Preclinical Cognition Model.

Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2.

Role of β-Arrestin2 Signaling in Neuropharmacological Effects of Psychedelic Drugs.

G2019S LRRK2 Kinase Inhibition in Heterozygous Mice Avoids Lung Phenotype Observed with Inhibition of WT LRRK2.

Modulating Stress Granules via HDAC6 Inhibition: A Promising Strategy against Alzheimer's Disease.

Microbes and Microbial Chemical Matter in the Seeding of Alzheimer's Disease: Prospects for Orthogonal Therapies.

Emerging Promise of Sulforaphane in Autism: A Comprehensive Review of Its Therapeutic Potential and Mechanisms.

Development of Aryl Cyano Amides for Fluorescence Discrimination of Tau and Amyloid Beta Deposits in Tissue.

Enhancing spin coherence of an optically addressed molecular qubit by nuclear spin hyperpolarization.

Real-Space Mapping of Emergent Correlated Electronic States With Scanning SQUID Microscopy.

Testing quantum-like markers in neural dynamics.

Linking Chemical Structure and Coherence Times of Molecular Spin Qubits.

Participation ratio as a quantum probe of hierarchical stickiness.

Hot Electrons Control of Quantum Dot Emission Using Plasmonic Supercells.

Related Experiment Videos

NeuroChat with Professor P. Jeffrey Conn

Related Concept Videos

Related Articles