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Surgery for Patients with Radiation-Induced Constrictive Pericarditis
Shixiong Wei1, Lin Zhang1, Huimin Cui1
1Department of Cardiovascular Surgery, PLA General Hospital, Institute of Cardiac Surgery, Beijing, China.
The Heart Surgery Forum
|January 3, 2020
Summary
Radiation-induced heart disease (RIHD) can develop after chest radiation therapy (RT). This report details two cases of radiation pericarditis, highlighting potential long-term cardiac complications and treatment options like pericardiectomy.
Area of Science:
- Cardiology
- Oncology
- Radiotherapy
Background:
- Chest radiation therapy (RT) is a critical treatment for various thoracic malignancies.
- Radiation-induced heart disease (RIHD) is a significant long-term complication of RT.
- The pericardium is particularly susceptible to radiation damage, potentially leading to pericarditis.
Observation:
- This report presents two cases of patients who developed radiation pericarditis following chest RT.
- Pericardial changes can manifest weeks after RT, with constrictive pericarditis developing over decades.
- The clinical presentation and progression of radiation-induced pericarditis can vary.
Findings:
- Radiation pericarditis is a recognized sequela of chest RT.
- Early pericardial changes may not immediately indicate severe long-term consequences.
- Delayed development of constrictive pericarditis is a characteristic feature.
Implications:
- Awareness of RIHD is crucial for oncologists and cardiologists managing patients post-RT.
- Long-term cardiac monitoring is essential for survivors of thoracic RT.
- Pericardiectomy remains an effective surgical intervention for advanced radiation-induced constrictive pericarditis.
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