Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

CNS Depressants: Barbiturates and Benzodiazepines01:14

CNS Depressants: Barbiturates and Benzodiazepines

1.1K
CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
1.1K
Anxiolytic Drugs: Benzodiazepines and Buspirone01:29

Anxiolytic Drugs: Benzodiazepines and Buspirone

2.2K
Benzodiazepines are a class of anxiolytic drugs known for their rapid efficacy and high therapeutic-to-lethal dose ratio, but with a potential risk of drug dependence. These drugs are lipophilic, allowing for rapid absorption after oral administration, eventually reaching the central nervous system (CNS). Once in the CNS, benzodiazepines bind to the allosteric site of the GABAA receptor. This binding enhances the inhibitory effects of the neurotransmitter GABA. By doing so, they prevent...
2.2K
Sedatives and Hypnotics Drugs: Benzodiazepines01:19

Sedatives and Hypnotics Drugs: Benzodiazepines

677
Benzodiazepines have both sedative and hypnotic properties. They include compounds such as diazepam (Valium) and alprazolam (Xanax). Structurally, their cores are similar, consisting of the fusion of a benzene ring and a diazepine ring, but they share a common mechanism of action in the central nervous system (CNS).
Benzodiazepines work by enhancing the effects of the inhibitory neurotransmitter GABA. They bind to the GABAA receptor, increasing its affinity for GABA, which opens chloride...
677
Anxiolytic Drugs: Overview01:26

Anxiolytic Drugs: Overview

949
Anxiolytic drugs are vital in managing anxiety disorders by effectively alleviating symptoms such as excessive fear, tachycardia, and tremors. There are several classes of anxiolytic medications, each with unique mechanisms of action and potential side effects.
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic...
949
Sedatives and Hypnotics: Overview01:23

Sedatives and Hypnotics: Overview

1.3K
Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics.
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
1.3K
Community Based Intervention01:30

Community Based Intervention

238
Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
238

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethical Dilemmas in School Nursing.

Narrative inquiry in bioethics·2026
Same author

Dignity of Risk, Intellectual/Developmental Disabilities, and Living in the Community.

Perspectives in biology and medicine·2022
Same author

An Educational Intervention for Mental Health Staff to Assess Clients' Diabetic Self-Care Skills for Self-Management and Safe Transition into the Community.

Journal of psychosocial nursing and mental health services·2021
Same author

Improving Referrals to Preschool Special Education in Pediatric Primary Care.

Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners·2021
Same author

Relationships among parenting stress, health-promoting behaviors, and health-related quality of life in Korean mothers of children with cerebral palsy.

Research in nursing & health·2020
Same author

Nurses' roles and challenges in providing end-of-life care in neonatal intensive care units in South Korea.

Applied nursing research : ANR·2019

Related Experiment Video

Updated: Dec 31, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K

An Intervention to Decrease Benzodiazepine Prescribing by Providers in an Urban Clinic.

Lois Platt, Teresa A Savage, Nimmi Rajagopal

    Journal of Psychosocial Nursing and Mental Health Services
    |January 3, 2020
    PubMed
    Summary

    This study reduced benzodiazepine (BZD) prescriptions by 80% using an educational intervention. The findings suggest this method effectively changes provider prescribing habits for BZDs.

    More Related Videos

    A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
    06:59

    A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

    Published on: November 9, 2016

    31.0K
    Improving IV Insulin Administration in a Community Hospital
    12:08

    Improving IV Insulin Administration in a Community Hospital

    Published on: June 11, 2012

    19.2K

    Related Experiment Videos

    Last Updated: Dec 31, 2025

    Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
    07:54

    Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

    Published on: December 6, 2016

    20.4K
    A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
    06:59

    A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

    Published on: November 9, 2016

    31.0K
    Improving IV Insulin Administration in a Community Hospital
    12:08

    Improving IV Insulin Administration in a Community Hospital

    Published on: June 11, 2012

    19.2K

    Area of Science:

    • Pharmacology
    • Medical Education
    • Quality Improvement

    Background:

    • Benzodiazepine (BZD) prescribing is a concern in outpatient settings.
    • There is a need for effective interventions to reduce BZD prescriptions.

    Purpose of the Study:

    • To decrease benzodiazepine (BZD) prescribing at a Midwestern university outpatient clinic.
    • To evaluate the effectiveness of a combined academic and pharmaceutical detailing intervention.

    Main Methods:

    • Providers received a brief, live educational intervention.
    • Intervention combined academic detailing (evidence-based information) and pharmaceutical detailing (sales techniques).
    • Prescribing data from electronic medical records were compared before and after the intervention.

    Main Results:

    • An 80% reduction in BZD prescribing was observed following the intervention.
    • The intervention significantly changed provider prescribing behavior.

    Conclusions:

    • Combined academic and pharmaceutical detailing is an effective strategy for modifying provider prescribing behavior regarding benzodiazepines (BZD).
    • Further research is necessary to confirm the sustainability of this change and ensure patient safety for those dependent on BZDs.