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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Smoking Status and Functional Outcomes After Acute Ischemic Stroke
Ryu Matsuo1,2, Tetsuro Ago1, Fumi Kiyuna1,2
1From the Department of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan. (R.M., T.A., F.K., N.S., K.N., J.K., Y.W., T.K.).
Stroke
|January 4, 2020
Summary
Current smoking and quitting smoking recently increases the risk of poor outcomes after acute ischemic stroke. Recent smokers face higher risks than those who quit longer ago.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Smoking is a known risk factor for stroke.
- The impact of prestroke smoking status on acute ischemic stroke outcomes remains unclear.
Purpose of the Study:
- To investigate the association between smoking status and functional outcomes in patients with acute ischemic stroke.
- To determine if current or past smoking affects recovery after stroke.
Main Methods:
- Analysis of a Japanese multicenter stroke registry (10,825 patients).
- Categorization of smoking status: never smoked, former smokers, current smokers.
- Logistic regression analysis adjusted for confounders to assess outcomes at 3 months (modified Rankin Scale).
Main Results:
- Current smokers had a higher odds ratio for poor functional outcome (OR 1.29) compared to never smokers.
- Former smokers who quit within 2 years of stroke onset showed increased risk (OR 1.75).
- Increased cigarette consumption correlated with higher poor outcome risk in current smokers.
Conclusions:
- Current smoking is linked to worse functional outcomes 3 months post-stroke.
- Recent smoking cessation (within 2 years) also associates with poorer outcomes.
- Smoking cessation timing is crucial for stroke recovery.
