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Updated: Dec 31, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
Published on: April 8, 2009
Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports
Litao Wang1, Yuwen Su2, Jianzhong Zhang1
1Department of Dermatology, Affiliated Hospital of Hebei University of Engineering, Handan 056002, Hebei, China.
Abstract:
Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α.
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