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Hepatic resection for primary and metastatic tumors
1Department of Surgery, St. Luke's/Roosevelt Hospital, New York, New York.
American Journal of Surgery
|November 1, 1988
Summary
Hepatic resection is a safe and effective treatment for liver tumors and metastases, offering improved long-term survival. This study shows acceptable morbidity and no operative deaths in 34 liver resections.
Area of Science:
- Hepatobiliary Surgery
- Surgical Oncology
- Gastroenterology
Background:
- Liver resections are performed for various conditions, including primary liver tumors, metastases, and benign lesions.
- Colorectal cancer is a common indication for liver metastasis resection.
Purpose of the Study:
- To evaluate the safety, morbidity, and survival outcomes of hepatic resections.
- To assess factors influencing survival in patients undergoing liver resection for metastatic colorectal cancer.
Main Methods:
- Retrospective analysis of 34 hepatic resections performed on 33 patients.
- Procedures included trisegmentectomies, lobectomies, segmentectomies, and wedge resections.
- Patient diagnoses included metastatic colorectal cancer, primary liver tumors, benign lesions, and trauma.
Main Results:
- No operative deaths occurred. Operative morbidity included subphrenic abscesses, bile leak, bile duct injury, cholestasis, and phlebitis.
- Median survival for metastatic colorectal cancer was 40 months, with a 5-year actuarial survival rate of 35%.
- Survival was not influenced by metastasis number or size but was better for Dukes' B vs. Dukes' C primary colorectal lesions.
Conclusions:
- Hepatic resection can be performed safely with acceptable morbidity.
- Liver resection offers improved long-term survival for selected patients, particularly those with metastatic colorectal cancer.
- Tumor stage of the primary colorectal lesion impacts survival outcomes.