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Related Concept Videos

Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

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Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
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Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
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Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

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Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
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Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Updated: Dec 31, 2025

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis
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[Acute necrotizing fasciitis complicated with multiple organ dysfunction: one case report].

Qiang Li1, Chao Li, Zongyu Wang

  • 1Department of Critical Care Medicine, Peking University Third Hospital, Beijing 100191, China. Corresponding author: Zhu Xi,

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
|January 4, 2020
PubMed
Summary

Early amputation and broad-spectrum antibiotics are crucial for rapidly progressing necrotizing fasciitis. This case study highlights successful treatment of a severe group A Streptococcal infection with comprehensive organ support.

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Pseudofracture: An Acute Peripheral Tissue Trauma Model
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Pseudofracture: An Acute Peripheral Tissue Trauma Model
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Area of Science:

  • Infectious Diseases
  • Surgical Critical Care

Background:

  • Acute necrotizing fasciitis requires prompt intervention, including surgical debridement and antibiotics.
  • Group A Streptococcus can cause severe, rapidly progressing infections.

Observation:

  • A 50-year-old male presented with acute necrotizing fasciitis of the right lower extremity due to group A Streptococcus.
  • The infection rapidly progressed, leading to septic shock and multiple organ dysfunction.

Findings:

  • The patient underwent right lower extremity amputation, received broad-spectrum antibiotics, gamma globulin, and continuous hemofiltration.
  • Comprehensive treatment resulted in successful patient recovery.

Implications:

  • Early amputation is vital for debriding infected lesions in rapidly advancing necrotizing fasciitis.
  • Aggressive antibiotic therapy and organ support are essential for managing severe streptococcal infections.