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Eruptive disseminated Spitz nevi - Case report.
Pablo Vargas1, Rodrigo Cárdenas2, Roberto Cullen1
1Department of Dermatology, Faculty of Medicine, University of Chile, Santiago, Chile.
Anais Brasileiros De Dermatologia
|January 4, 2020
Summary
Eruptive disseminated Spitz nevi is a rare condition presenting as numerous small lesions. This case highlights the diagnostic challenges and features of this benign melanocytic proliferation.
Area of Science:
- Dermatology
- Oncology
Background:
- Spitz nevi are benign melanocytic tumors with varied presentations.
- The disseminated eruptive form is rare and can be challenging to manage.
Observation:
- A 24-year-old patient presented with multiple papules on limbs over four years.
- Physical examination revealed 120 pink, skin-colored papules.
- Dermoscopy showed homogeneous, pink vascular lesions.
Findings:
- Histopathology revealed epithelioid cells in the dermis and dermo-epidermal junction.
- Immunohistochemistry showed HMB-45 positivity in superficial dermis.
- Ki-67 proliferation index was less than 1%.
Implications:
- Diagnosis requires careful clinical and histopathological correlation.
- Understanding eruptive disseminated Spitz nevi aids in appropriate patient management.
- Distinguishing from melanoma is crucial, though this variant is benign.

