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Differential Expression Gene Explorer (DrEdGE): a tool for generating interactive online visualizations of gene
Sophia C Tintori1, Patrick Golden2, Bob Goldstein1
1Department of Biology.
Bioinformatics (Oxford, England)
|January 4, 2020
Summary
Differential Expression Gene Explorer (DrEdGE) is a web tool enabling genomicists to create interactive visualizations for exploring gene expression data. This facilitates independent discovery of genes, samples, and patterns across various datasets.
Area of Science:
- Genomics
- Bioinformatics
- Data Visualization
Background:
- Large-scale genomics datasets are crucial for biological discovery.
- Exploring these datasets often requires specialized technical skills, limiting independent analysis.
- Interactive data visualization tools can enhance accessibility and facilitate gene discovery.
Purpose of the Study:
- To introduce Differential Expression Gene Explorer (DrEdGE), a web-based tool for creating interactive genomics data visualizations.
- To enable researchers to independently explore and query large genomics datasets for genes, samples, and patterns of interest.
- To lower technical barriers for accessing and analyzing complex biological data.
Main Methods:
- DrEdGE is a web-based platform for generating online data visualizations.
- Users can create interactive websites from genomics datasets.
- The tool allows colleagues to query visualizations based on specific conditions.
Main Results:
- DrEdGE successfully generated three example websites using publicly available datasets (human neuronal, mouse embryonic, and C. elegans).
- These examples demonstrate the tool's capability in visualizing and exploring differential gene expression.
- The platform effectively removes technical hurdles for data exploration.
Conclusions:
- DrEdGE enhances the utility of large genomics datasets by simplifying data exploration.
- The tool empowers genomicists to conduct independent analyses and discover novel biological insights.
- DrEdGE promotes wider accessibility to complex genomic information.
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