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Updated: Dec 31, 2025

A Protocol for Safe Lithiation Reactions Using Organolithium Reagents
Published on: November 12, 2016
Catechol Thioesters: Ligands for Hierarchically Formed Lithium-Bridged Titanium(IV) Helicates and Helicate-Based
A Carel N Kwamen1, Gilles S de Macedo1, Constanze Wiederhold2
1Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
Abstract:
The thioester moiety is introduced as a lithium binding unit for the hierarchical formation of titanium(IV) catecholate-based lithium-bridged helicates. In solution, the coordination compounds show a monomer-dimer equilibrium which -in comparison to the oxo esters- is significantly shifted towards the monomers. In addition, the influence of the thioester side chain on the dimerization behavior is investigated and an expansible/compressible molecular switch is synthesized. In the latter case expansion and compression are performed reversibly in methanol, whereas in DMSO spontaneous expansion occurs.
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