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Isolated myeloid sarcoma presenting with small bowel obstruction: a case report
Rie Mizumoto1, Masanori Tsujie1, Tomoko Wakasa2
1Department of Surgery, Kindai University Nara Hospital, 1248-1 Otoda, Ikoma, Nara, 630-0293, Japan.
Surgical Case Reports
|January 5, 2020
Summary
Myeloid sarcoma (MS), a rare tumor outside the bone marrow, can cause intestinal obstruction. Early diagnosis and systemic chemotherapy are crucial for treating this rare small bowel malignancy.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Myeloid sarcoma (MS) is a rare extramedullary tumor composed of myeloid blasts.
- MS typically presents as a solid tumor outside the bone marrow.
- Isolated MS of the small bowel is exceptionally rare.
Purpose of the Study:
- To report a rare case of isolated myeloid sarcoma of the small bowel.
- To highlight the diagnostic challenges and management of small bowel MS.
- To emphasize the importance of considering MS in the differential diagnosis of small bowel tumors.
Main Methods:
- Case presentation of a 54-year-old man with jejunal obstruction.
- Diagnostic workup included small bowel series and computed tomography.
- Surgical intervention involved laparoscopy-assisted partial jejunal resection with lymphadenectomy.
- Histopathological examination confirmed myeloid sarcoma.
Main Results:
- A jejunal tumor causing severe obstruction was identified.
- Histopathology confirmed the tumor as myeloid sarcoma.
- The patient's obstruction was successfully treated with surgical resection.
Conclusions:
- Myeloid sarcoma requires systemic chemotherapy, similar to acute myeloid leukemia.
- Early and accurate diagnosis of MS is imperative for effective treatment.
- MS should be included in the differential diagnosis of small bowel tumors, even in patients without a history of leukemia.

