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Updated: Dec 31, 2025

A Microplate Assay to Assess Chemical Effects on RBL-2H3 Mast Cell Degranulation: Effects of Triclosan without Use of an Organic Solvent
Published on: November 1, 2013
Fate, risk and removal of triclocarban: A critical review
Hui Yun1, Bin Liang2, Deyong Kong3
1Gansu Key Laboratory of Biomonitoring and Bioremediation for Environment Pollution, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, 730000, Gansu, China; Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Science, Lanzhou University, Tianshui South Road #222, Lanzhou, 730000, Gansu, China; Key Laboratory of Environmental Biotechnology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Abstract:
The halogenated antimicrobial triclocarban (TCC) has large production and consumption over last decades. Its extensive utilization in personal care products and insufficient treatment in conventional wastewater treatment plants (WWTPs) has led to its listing as one of emerging organic contaminants (EOCs). Due to the hydrophobicity and chemical stability of TCC, it has been omnipresent detected in terrestrial and aquatic environments, and its prolonged exposure has thrown potential pernicious threat to ecosystem and human health. Considering its recalcitrance, especially under anoxic conditions, both biological and non-biological methods have been exploited for its removal. The efficiency of advanced oxidation processes was optimistic, but complete removal can rarely be realized through a single method. The biodegradation of TCC either with microbial community or pure culture is feasible but efficient bacterial degraders and the molecular mechanism of degradation need to be further explored. This review provides comprehensive information of the occurrence, potential ecological and health effects, and biological and non-biological removal of TCC, and outlines future prospects for the risk evaluation and enhanced bioremediation of TCC in various environments.
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