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Published on: May 5, 2022
Risk factors for ocular complications in adult patients with uveitis
Mar Prieto-Del-Cura1,2, Juan Jacobo González-Guijarro1,3,4
1Department of Ophthalmology, Hospital Universitario de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
Purpose:
To report risk factors for ocular complications in adults with uveitis.
Methods:
Retrospective cohort study of 653 patients with uveitis (869 eyes) followed up for at least 1 month attended between May 1989 and December 2012.
Results:
After a median follow-up of 16 months (interquartile range = 3-59), 43.5% of patients developed one or more complications, including cataract formation (25%), iris alterations (20%), and macular edema (16%) as the most frequent. Older age, intermediate uveitis, chronic course, and uveitis activity >3 months were significantly more frequent among patients with complications. In the multivariate analysis, age ⩾65 years (hazard ratio = 2.76, 95% confidence interval = 1.72-4.4), chronic course (hazard ratio = 1.78, 95% confidence interval = 1.23-259), and uveitis activity >3 months (hazard ratio = 1.94, 95% confidence interval = 1.33-2.84) were predictors of complications.
Conclusion:
In the present series of patients with uveitis, advanced age, chronic uveitis, and inflammatory activity >12 weeks were risk factors for complications.
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