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Weight loss supplement causing acute heart block in a child
Daniel R O'Brien1, Vivian Szymczuk2, Cecilia A Albaro2
1Department of Internal Medicine/Pediatrics, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.
Insights
A teenager experienced severe heart block and toxicity after consuming a candlenut seed for weight loss. This case highlights the unknown risks of herbal supplements and the need for medical awareness.
Area of Science:
- Cardiology
- Toxicology
- Herbal Medicine
Background:
- Herbal weight loss supplements pose potential health risks.
- Aleurites moluccana (Candlenut) is used in traditional medicine and for weight loss.
- Adverse effects of herbal remedies are often underreported.
Observation:
- A 16-year-old male presented with vomiting, somnolence, and chest pain.
- Electrocardiogram revealed 2nd-degree heart block, worsening over time.
- Symptoms mimicked digoxin toxicity.
Findings:
- Ingestion of a single Aleurites moluccana seed led to significant cardiac toxicity.
- The patient's condition improved with supportive care in the ICU.
- Complete resolution of symptoms occurred within 48 hours.
Implications:
- Physicians must consider herbal supplement toxicity in patients with unexplained symptoms.
- Increased awareness and reporting of adverse events from herbal products are crucial.
- Further research is needed to understand the toxicological profiles of commonly used herbal supplements.
Abstract:
A 16-year-old male was admitted to the paediatric ICU with acute onset of vomiting, somnolence, and chest pain, and electrocardiogram showing 2nd degree heart block after ingesting an Aleurites moluccana (Candlenut) seed as a herbal weight loss supplement. Electrocardiogram showed progressively worsening heart block with down-sloping of the ST segments, resembling digoxin toxicity. After 2 days of ICU observation, his symptoms began to improve and eventually resolved. The side effects of herbal supplements are often unknown but by analysing cases such as these, physicians can develop a better understanding of these substances to help guide management.
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