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The Protective Effects of Myricetin against Cardiovascular Disease

Lu Wang1, Haiyan Wu1, Fei Yang2

  • 1Department of Pharmacy, Jinan Central Hospital Affiliated to Shandong University.

Journal of Nutritional Science and Vitaminology
|January 7, 2020
PubMed

Insights

Myricetin offers significant cardioprotective benefits, showing potential in preventing cardiovascular disease (CVD) and related complications. This natural compound demonstrates anti-hypertensive, anti-atherosclerotic, and anti-diabetic effects, supporting its clinical use.

Area of Science:

  • Cardiovascular Science
  • Pharmacology
  • Natural Products

Background:

  • Cardiovascular disease (CVD) is a major global health concern, representing a leading cause of death worldwide.
  • Myricetin has demonstrated promising protective effects against CVD in various in vitro and in vivo studies.

Purpose of the Study:

  • To review and synthesize existing literature on the protective roles of myricetin in preventing cardiovascular disease.
  • To explore the potential mechanisms of action underlying myricetin's therapeutic benefits.

Main Methods:

  • A comprehensive literature search was conducted, assessing studies published between 2009 and 2019.
  • The review focused on identifying and analyzing the cardioprotective, anti-hypertensive, anti-atherosclerotic, anti-hyperglycemic, and anti-hyperlipidemic effects of myricetin.

Main Results:

  • Myricetin exhibits multiple beneficial effects relevant to CVD prevention, including cardioprotection and blood pressure regulation.
  • The compound also demonstrated anti-atherosclerotic, anti-hyperglycemic, and anti-hyperlipidemic properties.
  • Myricetin may help alleviate complications associated with adult-onset diabetes, further contributing to CVD prevention.

Conclusions:

  • Myricetin possesses a range of therapeutic benefits that collectively support its potential for the clinical prevention of cardiovascular disease.
  • Further research into its mechanisms of action can bolster the evidence for its integration into CVD prevention strategies.

Keywords:
atheroscleroticcardioprotectivehypertensivehypoglycemichypolipidemic

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