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Updated: Dec 31, 2025

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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
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Contact lens fitting after corneal collagen cross-linking
Preeji Suderman Mandathara1, Parthasarathi Kalaiselvan1, Varsha M Rathi1,2
1Bausch and Lomb Contact Lens Clinic, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Oman Journal of Ophthalmology
|January 7, 2020
Summary
Corneal collagen cross-linking (CXL) did not significantly alter refraction or rigid gas permeable (RGP) lens parameters. However, RGP lenses remain crucial for visual acuity post-CXL in corneal ectasia patients.
Area of Science:
- Ophthalmology
- Corneal Ectasia Research
- Contact Lens Technology
Background:
- Contact lenses (CLs) are essential for vision correction in keratoconus.
- Corneal collagen cross-linking (CXL) is a common treatment for corneal ectasia.
- Assessing the impact of CXL on existing CL fitting is crucial.
Purpose of the Study:
- To evaluate changes in contact lens (CL) fitting after corneal collagen cross-linking (CXL).
- To determine if pre-existing CLs can be reused post-CXL.
Main Methods:
- Retrospective analysis of patient records from a tertiary center.
- Collected data included demographics, pre- and post-CXL refraction, corneal topography, and CL fitting details.
- Compared pre- and post-CXL data using descriptive analysis and paired t-tests.
Main Results:
- No significant changes in refraction or rigid gas permeable (RGP) lens parameters were observed post-CXL.
- Significant changes in RGP lens fitting characteristics were noted, indicating corneal shape alterations.
- Best spectacle-corrected visual acuity and RGP lens visual acuity showed no significant difference pre- and post-CXL.
Conclusions:
- Corneal collagen cross-linking (CXL) does not significantly alter refractive error or RGP lens parameters.
- Post-CXL corneal shape changes necessitate reassessment of RGP lens fitting.
- Rigid gas permeable (RGP) lenses are effective for visual rehabilitation after CXL in corneal ectasia.
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