A new tool for diagnosing parathyroid lesions: angio plus ultrasound imaging

Our aim was to examine the potential value of angio plus ultrasound imaging in diagnosing parathyroid lesions. Angio plus ultrasound imaging uses a new paradigm in Doppler performance, which allows for a better detection of flow in small vessels while maintaining workflow of conventional color flow imaging characteristics.

Thirty parathyroid lesions, composed of 26 histopathologically diagnosed adenoma and 4 hyperplasia (two hyperplasia in the same patient), from 29 consecutive patients (6 men and 23 women; median age: 53 years, range: 25-78 years) were evaluated using both color Doppler and angio plus ultrasound imaging. The polar vessel (visible or invisible), number and distribution (peripheral, central, and both) of blood flow signals were compared between the two techniques.

On color Doppler, the polar vessel was visible in 6 (20%) lesions. The median number of blood flow signals was 6 [3-23]. The distribution of peripheral, central and both was shown in 4 (13.3%), 9 (30%), and 15 (50%) lesions respectively, and no blood signals was shown in 2 (6.7%) lesions. On angio plus ultrasound imaging, the polar vessel was visible in 16 (53.3%) lesions. The median number of blood flow signals was 3 [0-18]. The distribution of peripheral, central and both was shown in 1 (3.3%), 4 (13.3%), and 25 (83.3%) lesions respectively. There was significant difference between color Doppler and angio plus ultrasound imaging in the detection of the polar vessel, number and distribution of blood flow signals.

The typical polar vessel and increased vascularity commonly associated with parathyroid lesions may be obtained with angio plus ultrasound imaging. Angio plus ultrasound imaging can improve the detection rate and distribution characteristics of blood flow signals of parathyroid lesions. Further research is needed to clarify the clinical meaning of increased blood flow information, such as the differentiation of parathyroid lesions from other lesions.