Peri-operative cardiac biomarker screening: a narrative review

S M Ruzycki1, M Prystajecky2, M R Driedger3

  • 1Department of Medicine, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, AB, Canada.

Anaesthesia
|January 7, 2020
PubMed

Insights

Cardiac biomarker testing offers superior peri-operative risk assessment compared to traditional functional tests. This approach improves prediction of patient outcomes and guides management strategies.

Area of Science:

  • Cardiology
  • Peri-operative Medicine
  • Risk Stratification

Background:

  • Traditional peri-operative risk estimation relies on pre-operative functional assessment.
  • Current guidelines recommend functional assessment for predicting postoperative complications.
  • Emerging evidence highlights limitations of functional assessment alone.

Purpose of the Study:

  • To review evidence supporting cardiac biomarker use in peri-operative risk estimation.
  • To compare cardiac biomarkers with traditional functional assessment methods.
  • To identify patient groups benefiting from cardiac biomarker screening and discuss management protocols.

Main Methods:

  • Systematic review of contemporary evidence on cardiac biomarker utility.
  • Comparative analysis of predictive accuracy between biomarker and functional assessments.
  • Discussion of clinical protocols for screening and management.

Main Results:

  • Cardiac biomarker measurement demonstrates superior predictive discrimination for peri-operative events.
  • Biomarker assessment incorporates the postoperative course, offering a more comprehensive risk profile.
  • Evidence supports expanded use of biomarkers in specific patient populations.

Conclusions:

  • Cardiac biomarkers represent a significant advancement over traditional functional assessments for peri-operative risk stratification.
  • Implementation of biomarker screening protocols can optimize patient management and improve outcomes.
  • Further research should focus on refining screening criteria and management strategies.

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