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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
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Association between left ventricular diastolic dysfunction and subclinical coronary artery calcification
Mohamad Jihad Mansour1,2, Elie Chammas1,2, Omar Hamoui2
1Division of Cardiology, Faculty of Medical Sciences, Lebanese University, Hadath, Lebanon.
Echocardiography (Mount Kisco, N.Y.)
|January 7, 2020
Summary
Diastolic dysfunction (DD) is linked to subclinical coronary artery calcification (CAC), even in younger patients. Assessing CAC may improve risk stratification in patients with normal ejection fraction and atypical symptoms.
Area of Science:
- Cardiology
- Radiology
- Preventive Medicine
Background:
- Diastolic dysfunction (DD) assessment is crucial for heart failure patients with normal ejection fraction (EF).
- Many patients with DD remain asymptomatic, complicating early detection.
- Computed tomography calcium scoring (CTCS) is used for coronary artery disease (CAD) risk assessment.
Purpose of the Study:
- To evaluate the association between diastolic dysfunction (DD) and subclinical coronary artery calcification (CAC).
Main Methods:
- Retrospective analysis of 191 patients undergoing echocardiography and CTCS.
- DD was assessed and graded using 2D and tissue Doppler imaging.
- Coronary artery calcium (CAC) scores were quantified.
Main Results:
- 36% of patients had DD. Higher CAC scores correlated with older age, comorbidities, and DD.
- DD was independently associated with subclinical atherosclerosis (CAC > 0) (OR 3.66).
- Patients with DD, especially those under 65, showed a significant increase in subclinical coronary atherosclerosis.
Conclusions:
- Diastolic dysfunction (DD) is strongly associated with coronary artery calcification (CAC > 0), particularly in patients under 65.
- Routine CAC assessment may be warranted for risk stratification in patients with normal EF and atypical symptoms.
Keywords:
atherosclerosiscomputed tomographycoronary artery calcium scorecoronary artery diseasediastolic dysfunctionechocardiographyMore Related Videos
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